Paul Moayyedi was involved in a large National Institute of Health funded multicentre randomized controlled trial of antidepressant therapy in functional dyspepsia led by the Mayo clinic. Premsyl Bercik has conducted a phase 2 randomized trial assessing a novel probiotic in patients with mood disorders and irritable bowel syndrome (IBS) and recently completed a pilot study showing the ability of a probiotic bacterium to improve depression in patients with IBS. He has also led a CIHR funded study that has evaluated a cohort of patients with IBS and correlated changes in symptoms with changes in the gut micro biome. John Marshall and Stephen Collins led a series of investigations on the impact of the large outbreak of water poisoning in the town of Walkerton, Ontarion and the development of post-infectious IBS. These studies described the epidemiology, pathophysiology and genetic predisposition to PI-IBS over an 8 year period.
People working in this area
Gastroenterology. Link: 25921377
Gastroenterology. Link: 24417817
Gastroenterology. Link: 23994201
Gut. Link: 20427395
Gastroenterology. Link: 20044998
Am J Gastroenterol. Link: 18371141