Systematic Reviews and Guidelines


McMaster University is the home of evidence-based medicine (EBM) and several members of the Farncombe Family Digestive Health Research Institute are internationally recognized for their EBM methodology.  Grigoris Leontiadis is the chair for the Canadian Association of Gastroenterology (CAG) Practice Affairs Committee.  He also is the methodology lead for all CAG guidelines including ulcerative colitis, quality indicators, and thromboembolism in inflammatory bowel disease (IBD).  Paul Moayyedi has been the methodology expert on several US guidelines including the American College of Gastroenterology guidelines on IBD, irritable bowel syndrome and functional constipation as well as the American Gastroenterology Association guidelines on the management of pancreatic cysts. Paul Moayyedi and Grigoris Leontiadis are joint Coordinating Editors of the Upper Gastrointestinal and Pancreatic Diseases Cochrane Review Group.  This supports all Cochrane Reviews that relate to upper GI or pancreatic diseases published in the Cochrane Library.  This is a library that provides the latest evidence on the efficacy of health care interventions for doctors and their patients worldwide. John Marshall conducts systematic reviews of IBD therapy such as 5ASA and ulcerative colitis rescue agents. He also leads development and dissemination of national and global clinical practice guidelines for IBD care.

People working in this area

Relevant Papers

  • American gastroenterological association technical review on the diagnosis and management of asymptomatic neoplastic pancreatic cysts. -
    Scheiman James M, Hwang Joo Ha, Moayyedi Paul et al.
    Gastroenterology. Link: 25805376
  • American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts. -
    Vege Santhi Swaroop, Ziring Barry, Jain Rajeev et al.
    Gastroenterology. Link: 25805375
  • American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. -
    Ford Alexander C, Moayyedi Paul, Lacy Brian E et al.
    Am J Gastroenterol. Link: 25091148
  • Canadian Association of Gastroenterology position statement: fecal microbiota transplant therapy. -
    Moayyedi Paul, Marshall John K, Yuan Yuhong et al.
    Can J Gastroenterol Hepatol. Link: 25232572
  • BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia. -
    Bennett Cathy, Moayyedi Paul, Corley Douglas A et al.
    Am J Gastroenterol. Link: 25869390
  • Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. -
    Ford Alexander C, Marwaha Avantika, Sood Ruchit et al.
    Gut. Link: 25147201
  • Canadian Association of Gastroenterology position statement: hip fracture and proton pump inhibitor therapy-a 2013 update. -
    Moayyedi Paul, Yuan Yuhong, Leontiadis Grigorios et al.
    Can J Gastroenterol. Link: 24251323
  • Optimum duration of regimens for Helicobacter pylori eradication. -
    Yuan Yuhong, Ford Alex C, Khan Khurram J et al.
    Cochrane Database Syst Rev. Link: 24338763
  • Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. -
    Ford Alexander C, Sandborn William J, Khan Khurram J et al.
    Am J Gastroenterol. Link: 21407183
  • Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. -
    Khan Khurram J, Ullman Thomas A, Ford Alexander C et al.
    Am J Gastroenterol. Link: 21407187

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