Associate Professor, Department of Medicine
Director, Gastroenterology Residency Training Program

Email: marshllj@mcmaster.ca

Year of appointment: 2000

Research Areas

Clinical outcomes research 

Focus

• Inflammatory bowel disease
• Post-infectious irritable bowel syndrome
• Gastrointestinal bleeding, clinical trials
• Clinical epidemiology
• Health outcomes
• Health economics

Selected Publications

• Thabane M, Simunovic MD, Akhtar-Danesh N, Garg AX, Clark WF, Collins SM, Salvadori M, Marshall JK. An Outbreak of Acute Bacterial Gastroenteritis Is Associated With an Increased Incidence of Irritable Bowel Syndrome in Children. Am J Gastroenterol 2010; 105(4): 933-9. PDF
• Marshall JK, Thabane M, Garg AX, Clark WF, Moayyedi P, Collins SM, Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery. Gut. 2010 59(5): 605-11. PDF
• Ford AC, Thabane M, Collins SM, Moayyedi P, Garg AX, Clark WF, Marshall JK. Prevalence of Uninvestigated Dyspepsia 8 Years After a Large Waterborne Outbreak of Bacterial Dysentery: A Cohort Study. Gastroenterology 2010; 138: 1727-1736. PDF
• Villani AC, Lemire M, Thabane M, Belisle A, Geneau G, Garg AX, Clark WF, Moayyedi P, Collins SM, Franchimont D, Marshall JK. Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis. Gastroenterology 2010; 138: 1502-1513. PDF
• Thabane M, Simunovic M, Akhtar-Danesh N, Marshall JK. Development and Validation of a Risk Score for Post-Infectious Irritable Bowel Syndrome. Am J Gastroenterol 2009; Epub.PDF
• Marshall DA, Johnson FR, Kulin NA, Ozdemir S, Walsh JM, Marshall JK, Van Bebber S, Phillips KA. How do physician assessments of patient preferences for colorectal cancer screening tests differ from actual preferences? A comparison in Canada and the United States using a stated-choice survey. Health Econ 2009; Epub. PDF
• Marshall JK. Post-infectious irritable bowel syndrome following water contamination. Kidney Int 2009; 112(S): 42-3. PDF
• Marshall JK. Review: azathioprine, infliximab, certolizumab, and adalimumab are effective for maintaining remission in Crohn's disease. Evid Based Med 2008; 13(4): 115. PDF
• Panaccione R, Fedorak RN, Aumais G, Bernard EJ, Bernstein CN, Bitton A, Croitoru K, Dieleman LA, Enns R, Feagan BG, Franchimont D, Greenberg GR, Griffiths AM, Marshall JK, Pare P, Patel S, Penner R, Render C, Seidman E, Steinhart AH. Review and clinical perspectives for the use of infliximab in ulcerative colitis. Can J Gastroenterol 2008; 22(3): 261-72. PDF
• Marshall DA, Johnson FR, Phillips KA, Marshall JK, Thabane L, Kulin NA. Measuring patient preferences for colorectal cancer screening using a choice-format survey. Value Health 2007; 10(5): 415-30. PDF
• Thabane M, Kottachchi DT, Marshall JK. Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome. Aliment Pharmacol Ther 2007; 26(4): 535-44. PDF
• Leonard J, Marshall JK, Moayyedi P. Systematic review of the risk of enteric infection in patients taking acid suppression. Am J Gastroenterol 2007; 102(9): 2047-56. PDF
• Comay D, Blackhouse G, Goeree R, Armstrong D, Marshall JK. Photodynamic therapy for Barrett's esophagus with high-grade dysplasia: a cost-effectiveness analysis. Can J Gastroenterol 2007; 21(4): 217-22. PDF
• Marshall JK, Thabane M, Borgaonkar MR, James C. Postinfectious irritable bowel syndrome after a food-borne outbreak of acute gastroenteritis attributed to a viral pathogen. Clin Gastroenterol Hepatol 2007; 5(4): 457-60. PDF
• Marshall JK. Finding inflammatory bowel disease genes will not lead to a cure. Can J Gastroenterol 2006; 20(10): 643-4. PDF
• Shirkey TW, Siggers RH, Goldade BG, Marshall JK, Drew MD, Laarveld B, Van Kessel AG. Effects of commensal bacteria on intestinal morphology and expression of proinflammatory cytokines in the gnotobiotic pig. Exp Biol Med 2006; 231(8): 1333-45. PDF
• Marshall JK, Thabane M, Garg AX, Clark WF, Salvadori M, Collins SM; Walkerton Health Study Investigators. Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery. Gastroenterology 2006; 131(2): 445-50. PDF
• Marshall JK. Reporting ileocolonoscopy in inflammatory bowel disease. Can J Gastroenterol 2006; 20(6): 399-400. PDF
• Borgaonkar MR, Ford DC, Marshall JK, Churchill E, Collins SM. The incidence of irritable bowel syndrome among community subjects with previous acute enteric infection. Dig Dis Sci 2006; 51(5): 1026-32. PDF
• Marshall JK, Thabane M, James C. Randomized active and placebo-controlled endoscopy study of a novel protected formulation of oral alendronate. Dig Dis Sci 2006; 51(5): 864-8. PDF
• Farrokhyar F, Marshall JK, Easterbrook B, Irvine EJ. Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: prevalence and impact on health. Inflamm Bowel Dis 2006; 12(1): 38-46. PDF
• Grootendorst PV, Marshall JK, Holbrook AM, Dolovich LR, O'Brien BJ, Levy AR. The impact of reference pricing of nonsteroidal anti-inflammatory agents on the use and costs of analgesic drugs. Health Serv Res 2005; 40(5): 1297-317. PDF
• Tu Y, Salim S, Bourgeois J, Di Leo V, Irvine EJ, Marshall JK, Perdue MH. CD23-mediated IgE transport across human intestinal epithelium: inhibition by blocking sites of translation or binding. Gastroenterology 2005; 129(3): 928-40. PDF
• Marshall JK, Gadowsky SL, Childs A, Armstrong D. Economic analysis of home vs hospital-based parenteral nutrition in Ontario, Canada. JPEN 2005; 29(4): 266-9. PDF
• Armstrong D, Marshall JK, Chiba N, Enns R, Fallone CA, Fass R, Hollingworth R, Hunt RH, Kahrilas PJ, Mayrand S, Moayyedi P, Paterson WG, Sadowski D, van Zanten SJ; Canadian Association of Gastroenterology GERD Consensus Group. Canadian Consensus Conference on the management of gastroesophageal reflux disease in adults - update 2004. Can J Gastroenterol 2005; 19(1): 15-35. PDF
• Marshall JK, Thabane M, Garg AX, Clark W, Meddings J, Collins SM; WEL Investigators. Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario. Aliment Pharmacol Ther 2004; 20(11-12): 1317-22. PDF
• Panaccione R, Fedorak RN, Aumais G, Bernstein CN, Bitton A, Croitoru K, Enns R, Feagan B, Fishman M, Greenberg G, Griffiths A, Marshall JK, Rasul I, Sadowski D, Seidman E, Steinhart H, Sutherland L, Walli E, Wild G, Williams CN, Zachos M; Canadian Association of Gastroenterology. Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease. Can J Gastroenterol 2004; 18(8): 503-8. PDF
• Marshall JK, Cawdron R, Zealley I, Riddell RH, Somers S, Irvine EJ. Prospective comparison of small bowel meal with pneumocolon versus ileo-colonoscopy for the diagnosis of ileal Crohn's disease. Am J Gastroenterol 2004; 99(7): 1321-9. PDF
• Marshall JK. Talk is cheap: The impact of consultation. Can J Gastroenterol 2004; 18(3): 181-2. PDF
• Greenwald E, Rawlinson JD, Marshall JK. A distinctive case of dysphagia. CMAJ 2004; 170(1): 42. PDF
• Barkun A, Bardou M, Marshall JK; Nonvariceal Upper GI Bleeding Consensus Conference Group. Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2003; 139(10): 843-57. PDF
• Comay D, Marshall JK. Resource utilization for acute lower gastrointestinal hemorrhage: the Ontario GI bleed study. Can J Gastroenterol 2002; 16(10): 677-82. PDF
• Marshall JK, Yamamura DL. A semiquantitative stool antigen test for Helicobacter pylori: shedding new light? J Clin Gastroenterol 2002; 35(5): 369-70. PDF
• Sumanac K, Zealley I, Fox BM, Rawlinson J, Salena B, Marshall JK, Stevenson GW, Hunt RH. Minimizing postcolonoscopy abdominal pain by using CO(2) insufflation: a prospective, randomized, double blind, controlled trial evaluating a new commercially available CO(2) delivery system. Gastrointest Endosc 2002; 56(2): 190-4. PDF
• Marshall JK, Grootendorst PV, O'Brien BJ, Dolovich LR, Holbrook AM, Levy AR. Impact of reference-based pricing for histamine-2 receptor antagonists and restricted access for proton pump inhibitors in British Columbia. CMAJ 2002; 166(13): 1655-62. PDF
• Marshall JK, Cawdron R, Yamamura DL, Ganguli S, Lad R, O'Brien BJ. Use and misuse of cost-effectiveness terminology in the gastroenterology literature: a systematic review. Am J Gastroenterol 2002; 97(1): 172-9. PDF
• Müller-Lissner SA, Bollani S, Brummer RJ, Coremans G, Dapoigny M, Marshall JK, Muris JW, Oberndorff-Klein Wolthuis A, Pace F, Rodrigo L, Stockbrügger R, Vatn MH. Epidemiological aspects of irritable bowel syndrome in Europe and North America. Digestion 2001; 64(3): 200-4. PDF
• Marshall JK, Pellissier JM, Attard CL, Kong SX, Marentette MA. Incremental cost-effectiveness analysis comparing rofecoxib with nonselective NSAIDs in osteoarthritis: Ontario Ministry of Health perspective. Pharmacoeconomics 2001; 19(10): 1039-49. PDF
• Marshall JK. LDP-02 (Millenium). Curr Opin Investig Drugs 2001; 2(4): 502-4. PDF
• Irvine EJ, Marshall JK. Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk. Gastroenterology 2000; 119(6): 1740-4. PDF
• Marshall JK, Irvine EJ. Lymphocytic and Collagenous Colitis: Medical Management. Curr Treat Options Gastroenterol 1999; 2(2): 127-133. PDF
• Marshall JK, Rainsford KD, James C, Hunt RH. A randomized controlled trial to assess alendronate-associated injury of the upper gastrointestinal tract. Aliment Pharmacol Ther 2000; 14(11): 1451-7. PDF
• Marshall JK, Irvine EJ. Putting rectal 5-aminosalicylic acid in its place: the role in distal ulcerative colitis. Am J Gastroenterol 2000; 95(7): 1628-36. PDF
• Marshall JK. A critical approach to clinical practice guidelines. Can J Gastroenterol 2000; 14(6): 505-9. PDF
• Marshall JK, Armstrong D, O'Brien BJ. Test and treat strategies for Helicobacter pylori in uninvestigated dyspepsia: a Canadian economic analysis. Can J Gastroenterol 2000; 14(5): 379-88. PDF
• Marshall JK, Lesi OA, Hunt RH. Obscure gastrointestinal bleeding: an approach to management. Can J Gastroenterol 2000; 14(2): 111-8. PDF

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