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David Armstrong, MA, MB BChir, FRCP, FRCPC, FACG, AGAF

Professor, Department of Medicine

Email: armstro@mcmaster.ca

  •  Upper gastrointestinal diseases including gastroesophageal reflux disease (GERD), Barrett’s esophagus, Helicobacter pylori-related disease and dyspepsia.
  • Nutrition, including home parenteral nutrition
  • Practice audit and education in endoscopy

Focus

  • Clinical studies in the management of GERD, Barrett’s esophagus and upper gastrointestinal bleeding
  • Studies of the symptomatology of gastrointestinal diseases including GERD, inflammatory bowel disease and the irritable bowel syndrome
  • The assessment of upper gastrointestinal tract sensitivity using barostat techniques and monitoring of heart rate variability
  • Pharmacological and physiological studies of gastric acidity
  • The clinical investigation of H. pylori infection using 13C Urea Breath
  • The endoscopic diagnosis of reflux esophagitis and Barrett’s esophagus
  • Practice audit in gastroenterology
  • Implementation of consensus recommendations in the management of Canadian patients with non-variceal upper gastrointestinal bleeding: A national cluster randomized trial of a tailored multifaceted intervention. October 2008- September 2010 Co-investigator (PI: ANG Barkun)
  • Quality of Care in Patients Admitted to Hospital Because of an Episode of GI Bleeding. July 2008 – June 2010. Co-Investigator (PI: ANG Barkun)
  • Vascular events in non-cardiac surgery patients cohort evaluation (VISION) Study. August 2007 – June 2009. Co-applicant (PI: PJ Devereaux) (Heart and Stroke Foundation of Ontario
  • Barrett’s esophagus registry — pilot for Canadian National Database. 2005-2008 (AstraZeneca Canada)
  • Histology of the Esophagus in Acid Related Disorders — The HEARD Study. 2005 — 2008 (AstraZeneca) — Principal Investigator
  1. Chen, JH, Parsons, SP, Shokrollahi, M, Wan, A, Vincent, AD, Yuan, Y et al.. Characterization of Simultaneous Pressure Waves as Biomarkers for Colonic Motility Assessed by High-Resolution Colonic Manometry. Front Physiol. 2018;9 :1248. doi: 10.3389/fphys.2018.01248. PubMed PMID:30294277 PubMed Central PMC6159752.
  2. Yongwen Ng, J, Chauhan, U, Armstrong, D, Marshall, J, Tse, F, Moayyedi, P et al.. A Comparison of the Prevalence of Anxiety and Depression Between Uncomplicated and Complex IBD Patient Groups. Gastroenterol Nurs. ;41 (5):427-435. doi: 10.1097/SGA.0000000000000338. PubMed PMID:30272605 .
  3. Negm, AM, Kennedy, CC, Ioannidis, G, Gajic-Veljanoski, O, Lee, J, Thabane, L et al.. Getting fit for hip and knee replacement: a protocol for the Fit-Joints pilot randomized controlled trial of a multi-modal intervention in frail patients with osteoarthritis. Pilot Feasibility Stud. 2018;4 :127. doi: 10.1186/s40814-018-0316-2. PubMed PMID:30038794 PubMed Central PMC6053795.
  4. Moayyedi, P, Veldhuyzen van Zanten, SJO, Hookey, L, Armstrong, D, Jones, N, Leontiadis, GI et al.. Proton pump inhibitors and gastric cancer: association is not causation. Gut. 2018; :. doi: 10.1136/gutjnl-2018-316958. PubMed PMID:30006494 .
  5. Libertucci, J, Dutta, U, Kaur, S, Jury, J, Rossi, L, Fontes, ME et al.. Inflammation-related differences in mucosa-associated microbiota and intestinal barrier function in colonic Crohn's disease. Am. J. Physiol. Gastrointest. Liver Physiol. 2018;315 (3):G420-G431. doi: 10.1152/ajpgi.00411.2017. PubMed PMID:29848021 .
  6. Dhaliwal, SK, Hunt, RH, Armstrong, D. Communicating Gastrointestinal Symptoms: The Patient's Challenge. Crit Rev Biomed Eng. 2018;46 (1):83-92. doi: 10.1615/CritRevBiomedEng.2018025987. PubMed PMID:29717678 .
  7. Fouda, MA, Khan, AA, Sultan, M, Rios, LP, McAssey, K, Armstrong, D et al.. Corrigendum to "Evaluation and Management of Skeletal Health in Celiac Disease: Position Statement". Can J Gastroenterol Hepatol. 2017;2017 :1323607. doi: 10.1155/2017/1323607. PubMed PMID:28752082 PubMed Central PMC5511633.
  8. Pinto-Sánchez, MI, Causada-Calo, N, Bercik, P, Ford, AC, Murray, JA, Armstrong, D et al.. Safety of Adding Oats to a Gluten-Free Diet for Patients With Celiac Disease: Systematic Review and Meta-analysis of Clinical and Observational Studies. Gastroenterology. 2017;153 (2):395-409.e3. doi: 10.1053/j.gastro.2017.04.009. PubMed PMID:28431885 .
  9. Tse, Y, Armstrong, D, Andrews, CN, Bitton, A, Bressler, B, Marshall, J et al.. Treatment Algorithm for Chronic Idiopathic Constipation and Constipation-Predominant Irritable Bowel Syndrome Derived from a Canadian National Survey and Needs Assessment on Choices of Therapeutic Agents. Can J Gastroenterol Hepatol. 2017;2017 :8612189. doi: 10.1155/2017/8612189. PubMed PMID:28271055 PubMed Central PMC5320366.
  10. Johnson, DA, Katz, PO, Armstrong, D, Cohen, H, Delaney, BC, Howden, CW et al.. The Safety of Appropriate Use of Over-the-Counter Proton Pump Inhibitors: An Evidence-Based Review and Delphi Consensus. Drugs. 2017;77 (5):547-561. doi: 10.1007/s40265-017-0712-6. PubMed PMID:28233274 PubMed Central PMC5357248.
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