Close

Grigorios Leontiadis, MD, PhD

Associate Professor, Department of Medicine

Email: leontia@mcmaster.ca

 

  • Etiology and pharmacologic management of acute peptic ulcer bleeding
  • Treatment of Helicobacter pylori infection
  • Prevention of upper gastrointestinal side-effects of non-steroidal anti-inflammatory drugs and anti-depressants
  • Adverse effects of acid-suppression medications
  • Diagnostic utility of video capsule endoscopy
  • Evolutionary medicine
  • Methodology of appraisal of the quality (trustworthiness) of evidence for systematic reviews and meta-analyses and for clinical practice guidelines

Closely tied to my research activities are my editorial roles. I am Joint Coordinating Editor of the Upper Gastrointestinal and Pancreatic Diseases Cochrane Review Group which is based at McMaster University, and Associate Editor of the American Journal of Gastroenterology and the Canadian Journal of Gastroenterology and Hepatology. I currently serve as Lead for Practice Affairs at the Canadian Association of Gastroenterology, responsible for ongoing clinical training, clinical practice-related issues, knowledge translation and dissemination and clinical practice guidelines. These editorial and administrative roles facilitate my continuing work on knowledge translation for patients and healthcare professionals. Knowledge translation has been defined by the Canadian Institutes of Health Research as “a dynamic and iterative process that includes synthesis, dissemination, exchange and ethically-sound application of knowledge to improve the health of Canadians, provide more effective health services and products and strengthen the health care system”.

AFP Internal Career Research Award, Department of Medicine, McMaster University. 2011-2014

CIHR Grant. Developing a tool for determining the risk of peptic ulcer complications with NSAIDS. Co-investigator. 2011 – 2012

NIHR Health Technology Assessment Programme (UK) Grant. Clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding. 2005-2007

  1. American Gastroenterological Association Institute Guideline on the Role of Upper Gastrointestinal Biopsy to Evaluate Dyspepsia in the Adult Patient in the Absence of Visible Mucosal Lesions. -
    Yang Yu-Xiao ,Brill Joel ,Krishnan Prashant ,Leontiadis Grigorios , - Gastroenterology. PubMed: PMID:26283143
  2. American Gastroenterological Association Institute Technical Review on the Role of Upper Gastrointestinal Biopsy to Evaluate Dyspepsia in the Adult Patient in the Absence of Visible Mucosal Lesions. -
    Allen John I ,Katzka David ,Robert Marie ,Leontiadis Grigorios I - Gastroenterology. PubMed: PMID:26278504
  3. Clinical practice guidelines for the medical management of nonhospitalized ulcerative colitis: the Toronto consensus. -
    Bressler Brian ,Marshall John K ,Bernstein Charles N ,Bitton Alain et al. - Gastroenterology. PubMed: PMID:25747596
  4. Canadian Association of Gastroenterology policy on the application for, and implementation of, clinical practice guidelines. -
    Singh Harminder ,Leontiadis Grigorios I ,Hookey Lawrence ,Enns Robert et al. - Canadian journal of gastroenterology & hepatology. PubMed: PMID:25314352
  5. Canadian Association of Gastroenterology position statement regarding the use of thiopurines for the treatment of inflammatory bowel disease. -
    Marshall John K ,Otley Anthony R ,Afif Waqqas ,Bernstein Charles N et al. - Canadian journal of gastroenterology & hepatology. PubMed: PMID:25157527
  6. Risk of upper gastrointestinal bleeding with selective serotonin reuptake inhibitors with or without concurrent nonsteroidal anti-inflammatory use: a systematic review and meta-analysis. -
    Anglin Rebecca ,Yuan Yuhong ,Moayyedi Paul ,Tse Frances ,Armstrong David ,Leontiadis Grigorios I - The American journal of gastroenterology. PubMed: PMID:24777151
  7. Consensus statements on the risk, prevention, and treatment of venous thromboembolism in inflammatory bowel disease: Canadian Association of Gastroenterology. -
    Nguyen Geoffrey C ,Bernstein Charles N ,Bitton Alain ,Chan Anthony K et al. - Gastroenterology. PubMed: PMID:24462530
  8. Optimum duration of regimens for Helicobacter pylori eradication. -
    Yuan Yuhong ,Ford Alex C ,Khan Khurram J ,Gisbert Javier P et al. - The Cochrane database of systematic reviews. PubMed: PMID:24338763
  9. Canadian Association of Gastroenterology position statement: hip fracture and proton pump inhibitor therapy-a 2013 update. -
    Moayyedi Paul ,Yuan Yuhong ,Leontiadis Grigorios , - Canadian journal of gastroenterology = Journal canadien de gastroenterologie. PubMed: PMID:24251323
  10. Guide wire-assisted cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. -
    Tse F ,Yuan Y ,Moayyedi P ,Leontiadis G I - Endoscopy. PubMed: PMID:23807804
  11. Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding. -
    Neumann Ignacio ,Letelier Luz M ,Rada Gabriel ,Claro Juan Carlos ,Martin Janet ,Howden Colin W ,Yuan Yuhong ,Leontiadis Grigorios I - The Cochrane database of systematic reviews. PubMed: PMID:23760821
  12. Effect of comorbidity on mortality in patients with peptic ulcer bleeding: systematic review and meta-analysis. -
    Leontiadis Grigorios I ,Molloy-Bland Michael ,Moayyedi Paul ,Howden Colin W - The American journal of gastroenterology. PubMed: PMID:23381016
  13. Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. -
    Tse Frances ,Yuan Yuhong ,Moayyedi Paul ,Leontiadis Grigorios I - The Cochrane database of systematic reviews. PubMed: PMID:23235679
  14. Conflicts of interest ethics: silencing expertise in the development of international clinical practice guidelines. -
    Jones Derek J ,Barkun Alan N ,Lu Yidan ,Enns Robert et al. - Annals of internal medicine. PubMed: PMID:22665816
  15. Canadian Association of Gastroenterology consensus guidelines on safety and quality indicators in endoscopy. -
    Armstrong David ,Barkun Alan ,Bridges Ron ,Carter Rose et al. - Canadian journal of gastroenterology = Journal canadien de gastroenterologie. PubMed: PMID:22308578
  16. Proton pump inhibitors and risk of fracture: a systematic review and meta-analysis of observational studies. -
    Ngamruengphong Saowanee ,Leontiadis Grigorios I ,Radhi Saba ,Dentino Andrew ,Nugent Kenneth - The American journal of gastroenterology. PubMed: PMID:21483462
  17. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. -
    Sreedharan Aravamuthan ,Martin Janet ,Leontiadis Grigorios I ,Dorward Stephanie ,Howden Colin W ,Forman David ,Moayyedi Paul - The Cochrane database of systematic reviews. PubMed: PMID:20614440
  18. Systematic review of the symptom burden, quality of life impairment and costs associated with peptic ulcer disease. -
    Barkun Alan ,Leontiadis Grigorios - The American journal of medicine. PubMed: PMID:20362756
  19. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. -
    Barkun Alan N ,Bardou Marc ,Kuipers Ernst J ,Sung Joseph ,Hunt Richard H ,Martel Myriam ,Sinclair Paul , - Annals of internal medicine. PubMed: PMID:20083829
Share on FacebookTweet about this on TwitterShare on Google+Share on LinkedIn