Maria Ines Pinto-Sanchez MD, MSc, CNSC

Assistant Professor, Division of Gastroenterology, Department of Medicine
McMaster University Medical Centre, Rm 3N8C
1280 Main Street West, Hamilton, ON L8S 4K1
Tel # 905-525-9140 x 22278

Clinical Interests

  • Celiac disease and gluten-related disorders
  • Functional gastrointestinal disorders
  • Enteral and parenteral nutrition
  • Intestinal failure

Research Interests

  • Clinical and translational research in celiac disease and gluten related disorders, nutrition, microbiology and gut brain axis
  • Systematic reviews and meta-analyses

Educational and professional standing

Dr. Maria Ines Pinto-Sanchez obtained her MD certification at the University of Cordoba, Argentina in 2002, and completed her Gastroenterology training in 2008 at Dr. C. B. Udaondo Gastroenterology Hospital in Buenos Aires, Argentina. She joined the Farncombe Institute in 2010 as clinical research fellow and obtained a Master in Science degree from the Health Research and Methodology program in 2014. She was clinical gastroenterology and nutrition fellow at McMaster from 2015 to 2017, during which time she contributed to the establishment of the first specialized Celiac Clinic for adult patients in Canada, led Dr. P. Bercik.

Dr. Pinto-Sanchez is currently an active medical staff at the Gastroenterology Division at McMaster University and Hamilton Health Sciences where she provides consultation services in the area of gastroenterology and nutrition.  Her clinical and research interest include the diagnosis and treatment of celiac disease, irritable bowel syndrome, gluten sensitivity and disorders of the microbiota gut-brain axis. She is a member of the Research Committee of the Canadian Association of Gastroenterology, Treasurer of the North American Society of the Study of Celiac Disease and has received many early career awards.

  1. Pinto-Sanchez MI, et al. Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: A pilot study in patients with irritable bowel syndrome. Gastroenterology. 2017 Aug;153(2):448-459.e8.
  2. Pinto-Sanchez MI, et al. Safety of Adding Oats to a Gluten-Free Diet for Patients With Celiac Disease: Systematic Review and Meta-analysis of Clinical and Observational Studies. Gastroenterology. 2017 Aug;153(2):395-409.e3.
  3. Pinto-Sanchez MI, et al. Proton pumps inhibitors for Functional Dyspepsia. Cochrane Database Syst Rev. 2017 Nov 21;11:CD011194.
  4. Duerksen D, Pinto-Sanchez MI, et al. Management of Bone Health in Patients with Celiac Disease: A Practical Guide for Clinicians. Canadian Family Physician 2017. In press.
  5. Simpkins S, Pintos-Sanchez, et al. Poor predictive value of lower gastrointestinal alarm features in the diagnosis of colorectal cancer in 1981 patients in secondary care. Aliment Pharmacol Ther. 2017 Jan;45(1):91-99.
  6. Irvine A, Pinto-Sanchez MI, et al. Minimal differences in prevalence and spectrum of organic disease at upper gastrointestinal endoscopy between selected secondary care patients with symptoms of gastro-oesophageal reflux or dyspepsia. Scand J Gastroenterol 2017;52:396-402.
  7. De Palma G, Lynch MDJ, Lu J, Dang VT,… Pinto- Sanchez MI, .. Bercik P. Microbiota from Irritable bowel syndrome patients with diarrhea and comorbid anxiety alters gut and brain function of gnotobiotic mice. Sci Transl Med. 2017 Mar 1;9(379).
  8. Pinto Sanchez MI, et al. infantis NLS super strain reduces expression of α-defensin-5,a marker of innate immunity, in the mucosa of active celiac disease patients. J Clin Gastroenterol. 2017 Oct;51(9):814-817.
  9. Pinto-Sanchez MI, Verdu EF. Non-celiac gluten sensitivity: Are we closer to separating the wheat from the chaff? Gut. 2016; 65 1930-1937
  10. Volta U, Pinto Sanchez MI, et al. Dietary triggers in irritable bowel syndrome: Is there a role for gluten? Journal of Neurogastroenterol Motil 2016; 22(4): 547-57.
  11. Pinto-Sánchez MI,et al. Altered esophageal mucosal structure in patients with celiac disease. Can J Gastroenterol Hepatol. 2016; 2016:1980686.
  12. Pinto-Sanchez MI, et al. Gluten Introduction to Infant Feeding and Risk of Celiac Disease: Systematic Review and Meta-Analysis. J Pediatrics 2015; 168:134-43.
  13. Pinto Sanchez MI, Bercik P, Verdu EF. Motility alterations in celiac disease and non-celiac gluten sensitivity. Dig Dis 2015; 33(2):200-7.
  14. Natividad JM, Pinto-Sanchez MI, et al. Ecobiotherapy rich in Firmicutes decreases susceptibility to colitis in a humanized gnotobiotic mouse model. Inflammatory bowel Diseases 2015; 21(8): 1883-93.
  15. Smecuol E, Pinto-Sanchez MI, Bai JC. Understanding the role of probiotics in coeliac disease. British Journal of Nutrition 2015; 28;113(10):1664-5.
  16. Pinto Sanchez MI, Bercik P, Verdu E, Bai JC. Extraintestinal manifestations of celiac disease. Dig Dis. 2015; 33(2): 147-54.
  17. Pinto-Sanchez MI, et al. Anxiety and depression increase in a stepwise manner in parallel with multiple FGIDs and symptom severity and frequency. Am J Gastroenterol 2015;110(7): 1038- 48.
  18. Pinto Sanchez MI, et al. A comparison of tax deductible provisions for the gluten- free diet with systems for GFD coverage available in various countries. Can J Gastroenterol Hepatol 2015;29(2): 104-10.
  19. Sanchez MI, Bercik P. Epidemiology and burden of chronic constipation. Can J Gastroenterol 2011;25(suppl B
  20. Sánchez MI, et al. Risk of fracture in celiac disease: gender, dietary compliance, or both? World J Gastroenterol.17(25): 3035-42.
  21. Smecuol E, Pinto Sanchez MI et al. Low-dose aspirin affects the small bowel mucosa: results of a pilot study with a multidimensional assessment. Clin Gastroenterol Hepatol 2009.7(5): 524-9.
  22. Pinto Sánchez MI, et al. Very high rate of misdiagnosis of celiac disease in clinical practice. Acta Gastroenterol Latinoam 2008;39(4): 250-3.
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